Switching Cadillac Bose Speakers to My Honda Civic?

Hello, my mom owns a 2004 Cadillac Escalade. Needless to say, she does not own the vehicle because of the sound quality, although the Bose speakers in the Escalade are incredible. I was wondering if it is possible to switch those speakers and put them in My 2008 Honda Civic that I just bought. If not, any ideas on optimizing my sound because I want a kick *** sound system (I already have a subwoofer with monoblock amp)